Uso terapêutico do óleo de canabidiol, análise das aplicações clínicas e efeito terapêuticos

Abstract

Introduction and objectives: Cannabis sativa is recognized in the United State Pharmacopeia. The medicinal demand for compounds from this plant has increased by 700% since 2015, according to Anvisa. In veterinary medicine, there has been an increase in the therapeutic use of Cannabis sativa, in the treatment of various conditions, being used mainly for the treatment of epilepsy, chronic pain, behavioral disorders. The present review aims to describe studies and uses of the cannabidiol component in the treatment of diseases in dogs. Result: Cannabis sativa has substances that have therapeutic properties, including more than 100 organic cannabinoid compounds. Among the cannabinoid compounds, the best known are THC and cannabidiol. Cannabidiol (CBD) is a therapeutic compound from Cannabis sativa, used in the treatment of pain relief, reducing inflammation, combating anxiety, improving sleep and helping with seizures without causing psychoactive effects. The endocannabinoid system (ECS), discovered in the 90s, is influenced by CBD due to endogenous receptors present in the cell membranes of various tissues, such as the brain, connective tissue, glands and immune system. Conclusion: The use of CBD in veterinary medicine is still little discussed due to the small number of studies on animals and consequently the complete understanding of the entire mechanism of action.